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BOOK SUMMARY :

Targeting inammation in cancer prevention and therapy jelena todoric12 laura antonucci1 and michael karin13 abstract inammation is associated with the development and malig nant progression of most cancers as most of the cell types involved in cancer associated inammation are genetically sta targeted drug strategies for cancer and inflammation editors jackman ann l leamon christopher p eds free preview describes the emerging range of therapeutics with the potential to more precisely target pathologic tissue recounts progress in the use of folates to transport antifolate drugs such as raltitrexed and pemetrexed that get this from a library targeted drug strategies for cancer and inflammation ann l jackman christopher p leamon the discoveries highlighted in this book parallel the emergence of innovative molecular targeted small molecules and monoclonal antibodies ie agents that target proteins within highly activated the discoveries highlighted in this book parallel the emergence of innovative molecular targeted small molecules and monoclonal antibodies ie agents that target proteins within highly activated sthese opportunities include epr effect high interstitial pressure of tumour low ph of endosomes of tumor cells overexpressed receptors angiogenesis etc chemotherapy is one of the most important treatments currently available among the various approaches the present status of chemotherapy is far from being satisfactory

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